Eunice L Kwak Selected Research

IMO-2055

4/2015

Open-label phase 1b study of FOLFIRI plus cetuximab plus IMO-2055 in patients with colorectal cancer who have progressed following chemotherapy for advanced or metastatic disease.

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Eunice L Kwak Research Topics

Disease

48	Neoplasms (Cancer) 01/2022 - 05/2005
15	Adenocarcinoma 07/2019 - 07/2006
13	Pancreatic Neoplasms (Pancreatic Cancer) 07/2019 - 07/2006
8	Colorectal Neoplasms (Colorectal Cancer) 01/2018 - 01/2012
6	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2014 - 10/2010
5	Fatigue 10/2020 - 06/2009
5	Neoplasm Metastasis (Metastasis) 01/2017 - 12/2007
5	Lung Neoplasms (Lung Cancer) 01/2014 - 05/2005
4	Stomach Neoplasms (Stomach Cancer) 11/2016 - 10/2014
4	Cholangiocarcinoma 02/2016 - 01/2012
4	Nausea 01/2015 - 02/2011
3	Diarrhea 10/2020 - 01/2014
3	Hyperglycemia 09/2017 - 11/2011
3	Fibrosis (Cirrhosis) 01/2017 - 01/2014
3	Esophageal Neoplasms (Esophageal Cancer) 11/2016 - 01/2013
3	Hepatocellular Carcinoma (Hepatoma) 02/2016 - 06/2009
3	Disease Progression 12/2015 - 01/2012
3	Neutropenia 10/2012 - 06/2009
2	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 01/2019 - 01/2012
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 04/2017 - 01/2012
2	Carcinogenesis 04/2015 - 02/2006
2	Vomiting 01/2015 - 02/2011
2	Stomatitis 01/2015 - 01/2014
2	Breast Neoplasms (Breast Cancer) 01/2014 - 02/2006
2	Anemia 01/2014 - 11/2011
2	Lymphopenia (Lymphocytopenia) 10/2012 - 11/2011
2	Ovarian Neoplasms (Ovarian Cancer) 02/2011 - 07/2005
2	Hypertension (High Blood Pressure) 02/2011 - 01/2010
1	Microsatellite Instability 01/2016
1	Melanoma (Melanoma, Malignant) 12/2015
1	Giant Cell Tumors (Giant Cell Tumor) 07/2015
1	Giant Cell Tumor of Tendon Sheath 07/2015
1	Pancreatic Fistula (Pancreatic Fistulas) 01/2015
1	Inflammation (Inflammations) 01/2015

Drug/Important Bio-Agent (IBA)

9	CrizotinibIBA 01/2020 - 10/2010
6	Pharmaceutical PreparationsIBA 10/2020 - 02/2011
6	Capecitabine (Xeloda)FDA Link 07/2019 - 07/2006
6	Biomarkers (Surrogate Marker)IBA 01/2016 - 12/2007
6	ErbB Receptors (EGF Receptor)IBA 01/2014 - 05/2005
5	Irinotecan (Camptosar)FDA LinkGeneric 07/2019 - 01/2012
5	folfirinoxIBA 07/2019 - 01/2013
4	Alanine Transaminase (SGPT)IBA 01/2020 - 01/2010
4	Oxaliplatin (Eloxatin)FDA LinkGeneric 07/2019 - 01/2010
4	Protons (Proton)IBA 07/2019 - 01/2014
4	Cetuximab (Erbitux)FDA Link 02/2016 - 01/2012
4	Proteins (Proteins, Gene)FDA Link 01/2016 - 07/2005
3	Fluorouracil (Carac)FDA LinkGeneric 07/2019 - 01/2013
3	Biological ProductsIBA 07/2018 - 07/2006
3	Gemcitabine FDA Link 01/2018 - 10/2007
3	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 09/2015 - 01/2012
3	Phosphotransferases (Kinase)IBA 07/2015 - 05/2005
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2015 - 01/2013
3	Tyrosine Kinase InhibitorsIBA 01/2014 - 05/2005
3	Anaplastic Lymphoma KinaseIBA 01/2013 - 10/2010
3	Erlotinib Hydrochloride (CP 358,774)FDA Link 10/2007 - 05/2005
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 10/2020 - 01/2013
2	Leucovorin (Folinic Acid)FDA Link 07/2019 - 01/2013
2	Cell-Free Nucleic AcidsIBA 01/2019 - 01/2018
2	Protein Isoforms (Isoforms)IBA 09/2017 - 01/2015
2	Messenger RNA (mRNA)IBA 01/2016 - 06/2008
2	TOR Serine-Threonine KinasesIBA 01/2014 - 11/2011
2	temsirolimus FDA Link 01/2014 - 09/2008
2	neratinibIBA 01/2014 - 05/2005
2	human ERBB2 proteinIBA 08/2013 - 01/2013
2	Everolimus FDA Link 01/2013 - 11/2011
2	Gefitinib (Iressa)FDA Link 07/2006 - 05/2005
1	spartalizumabIBA 01/2022
1	STA 9090IBA 10/2020
1	Losartan (Cozaar)FDA LinkGeneric 07/2019
1	AMG 337IBA 04/2019
1	130-nm albumin-bound paclitaxelIBA 01/2018
1	serabelisibIBA 09/2017
1	N-acetyltalosaminuronic acid (NAT)IBA 04/2016
1	Cytidine Triphosphate (CTP)IBA 02/2016
1	Cadherins (E-Cadherin)IBA 01/2016
1	Circulating Tumor DNAIBA 12/2015
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2015
1	Mitogen-Activated Protein KinasesIBA 12/2015
1	trametinibIBA 12/2015
1	dabrafenibIBA 12/2015
1	pexidartinibIBA 07/2015
1	Macrophage Colony-Stimulating FactorIBA 07/2015
1	cabozantinibIBA 04/2015
1	IMO-2055IBA 04/2015
1	gedatolisibIBA 01/2015
1	LactonesIBA 06/2014
1	CamptothecinIBA 06/2014

Therapy/Procedure

21	Therapeutics 01/2022 - 10/2007
9	Neoadjuvant Therapy 07/2019 - 06/2012
9	Radiotherapy 01/2018 - 01/2012
8	Drug Therapy (Chemotherapy) 07/2019 - 09/2007
3	Chemoradiotherapy 07/2019 - 01/2018
3	Proton Therapy 02/2016 - 01/2011
2	Adjuvant Chemotherapy 01/2018 - 03/2014
2	Operative Surgical Procedures 11/2016 - 04/2016
2	Lymph Node Excision (Lymph Node Dissection) 04/2016 - 01/2016
2	Gastrectomy 01/2016 - 10/2013
1	Splenectomy 04/2016
1	Operative Time 01/2015
1	Pancreaticoduodenectomy 07/2014